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Utilizing structure based drug design and metabolic soft sp..:

Hopkins, Brian T. ; Bame, Eris ; Bell, Noah...
Bioorganic & Medicinal Chemistry. 44 (2021) - p. 116275 , 2021

Link: https://doi.org/10.1016/j.bmc.2021.116275

RT Journal
T1 <Title>Utilizing structure based drug design and metabolic soft spot identification to optimize the in vitro potency and in vivo pharmacokinetic properties leading to the discovery of novel reversible Bruton's tyrosine kinase inhibitors</Title>

UL https://suche.suub.uni-bremen.de/peid=cr-10.1016_j.bmc.2021.116275&Exemplar=1&LAN=DE
				
A1 Hopkins, Brian T.
A1 Bame, Eris
A1 Bell, Noah
A1 Bohnert, Tonika
A1 Bowden-Verhoek, Jon K.
A1 Bui, Minna
A1 Cancilla, Mark T.
A1 Conlon, Patrick
A1 Cullen, Patrick
A1 Erlanson, Daniel A.
A1 Fan, Junfa
A1 Fuchs-Knotts, Tarra
A1 Hansen, Stig
A1 Heumann, Stacey
A1 Jenkins, Tracy J.
A1 Gua, Chuck
A1 Liu, Ying
A1 Liu, YuTing
A1 Lulla, Mukush
A1 Marcotte, Douglas
A1 Marx, Isaac
A1 McDowell, Bob
A1 Mertsching, Elisabeth
A1 Negrou, Ella
A1 Romanowski, Michael J.
A1 Scott, Daniel
A1 Silvian, Laura
A1 Yang, Wenjin
A1 Zhong, Min
PB Elsevier BV
YR 2021
SN 0968-0896
JF Bioorganic & Medicinal Chemistry
VO 44
SP 116275
LK http://dx.doi.org/https://doi.org/10.1016/j.bmc.2021.116275
DO https://doi.org/10.1016/j.bmc.2021.116275
SF ELIB - SuUB Bremen

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