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Lactams as EP4 prostanoid receptor subtype selective agonis..:

Elworthy, Todd R. ; Kertesz, Denis J. ; Kim, Woongki...
Bioorganic & Medicinal Chemistry Letters.  14 (2004)  7 - p. 1655-1659 , 2004
Link: https://doi.org/10.1016/j.bmcl.2004.01.063