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Discovery of novel, potent, and orally active spiro-urea hu..:

Shen, Dong-Ming ; Zhang, Fengqi ; Brady, Edward J....
Bioorganic & Medicinal Chemistry Letters.  15 (2005)  20 - p. 4564-4569 , 2005
Link: https://doi.org/10.1016/j.bmcl.2005.06.101