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Androstene-3,5-dienes as ER-β selective SERMs:

Blizzard, Timothy A. ; Gude, Candido ; Morgan II, Jerry D....
Bioorganic & Medicinal Chemistry Letters.  17 (2007)  22 - p. 6295-6298 , 2007
Link: https://doi.org/10.1016/j.bmcl.2007.09.001