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Pyrazinoindolone inhibitors of MAPKAP-K2:

Goldberg, D.R. ; Choi, Y. ; Cogan, D....
Bioorganic & Medicinal Chemistry Letters.  18 (2008)  3 - p. 938-941 , 2008
Link: https://doi.org/10.1016/j.bmcl.2007.12.037