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Benzo[c][2,7]naphthyridines as inhibitors of PDK-1:

Kim, Kyung-Hee ; Wissner, Allan ; Floyd Jr., Middleton B....
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  17 - p. 5225-5228 , 2009
Link: https://doi.org/10.1016/j.bmcl.2009.07.007