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Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Ra..:

Berger, Dan M. ; Torres, Nancy ; Dutia, Minu...
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  23 - p. 6519-6523 , 2009
Link: https://doi.org/10.1016/j.bmcl.2009.10.049