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Discovery of aminoheterocycles as potent and brain penetran..:

Wu, Zhicai ; Yang, Cangming ; Graham, Thomas H....
Bioorganic & Medicinal Chemistry Letters.  22 (2012)  4 - p. 1727-1730 , 2012
Link: https://doi.org/10.1016/j.bmcl.2011.12.098