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Macrocyclic prolinyl acyl guanidines as inhibitors of β-sec..:

Boy, Kenneth M. ; Guernon, Jason M. ; Wu, Yong-Jin...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  22 - p. 5040-5047 , 2015
Link: https://doi.org/10.1016/j.bmcl.2015.10.031