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An alternative single dose parameter to avoid the need for ..:

Paixão, Paulo ; Gouveia, Luís F. ; Morais, José A.G.
European Journal of Pharmaceutics and Biopharmaceutics.  80 (2012)  2 - p. 410-417 , 2012
Link: https://doi.org/10.1016/j.ejpb.2011.11.001