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Influence of the skin barrier on the penetration of topical..:

Yamamoto, K. ; Klossek, A. ; Flesch, R....
European Journal of Pharmaceutics and Biopharmaceutics.  118 (2017)  - p. 30-37 , 2017
Link: https://doi.org/10.1016/j.ejpb.2016.12.005