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Nonionic surfactants are strong inhibitors of cytochrome P4..:

Ren, Xiuhua ; Mao, Xinliang ; Cao, Lei...
European Journal of Pharmaceutical Sciences.  36 (2009)  4-5 - p. 401-411 , 2009
Link: https://doi.org/10.1016/j.ejps.2008.11.002