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FMISO-PET reflects not only hypoxia but also cell prolifera..:

Sato, J. ; Kitagawa, Y. ; Watanabe, S....
International Journal of Oral and Maxillofacial Surgery.  44 (2015)  - p. e135 , 2015
Link: https://doi.org/10.1016/j.ijom.2015.08.777