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MMP-8 and TIMP-1 are associated to periodontal inflammation..:

Schmalz, G. ; Davarpanah, I. ; Jäger, J....
Journal of Microbiology, Immunology and Infection.  52 (2019)  3 - p. 386-394 , 2019
Link: https://doi.org/10.1016/j.jmii.2017.07.016