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Cumulative nonsmoking risk factors increase the probability..:

Bravo-Iñiguez, Carlos E. ; Fox, Sam W. ; De Leon, Luis E....
The Journal of Thoracic and Cardiovascular Surgery.  158 (2019)  4 - p. 1248-1254.e1 , 2019
Link: https://doi.org/10.1016/j.jtcvs.2019.04.098