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The aldo-keto reductase AKR1C3 contributes to 7,12-dimethyl..:

Birtwistle, Jane ; Hayden, Rachel E. ; Khanim, Farhat L....
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis.  662 (2009)  1-2 - p. 67-74 , 2009
Link: https://doi.org/10.1016/j.mrfmmm.2008.12.010