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High leptin status indicates an increased risk of mortality..:

Mayer Jr., Otto ; Bruthans, Jan ; Seidlerová, Jitka...
Nutrition, Metabolism and Cardiovascular Diseases.  32 (2022)  9 - p. 2137-2146 , 2022
Link: https://doi.org/10.1016/j.numecd.2022.06.006