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Tryptophan via serotonin/kynurenine pathways abnormalities ..:

Comai, Stefano ; Bertazzo, Antonella ; Vachon, Jeanne...
Progress in Neuro-Psychopharmacology and Biological Psychiatry.  70 (2016)  - p. 8-16 , 2016
Link: https://doi.org/10.1016/j.pnpbp.2016.04.012