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2,3,7,8-Tetrachlorodibenzo-p-dioxin specifically reduces mR..:

KIUKKONEN, A ; SAHLBERG, C ; LUKINMAA, P...
Toxicology and Applied Pharmacology.  216 (2006)  3 - p. 399-406 , 2006
Link: https://doi.org/10.1016/j.taap.2006.06.015