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Isoforms of hyaluronidases can be a predictor of a prostate..:

de Sá, Vanessa K. ; Canavez, Flávio C. ; Silva, Iran A...
Urologic Oncology: Seminars and Original Investigations.  27 (2009)  4 - p. 377-381 , 2009
Link: https://doi.org/10.1016/j.urolonc.2008.04.013