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Increased nondisjunction of chromosome 21 with age in human..:

Shi, Qinghua ; Chen, Jianfang ; Adler, Ilse-Dore...
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis.  452 (2000)  1 - p. 27-36 , 2000
Link: https://doi.org/10.1016/s0027-5107(00)00032-4