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Spermine increases phosphatidylinositol 4,5-bisphosphate co..:

Coburn, Ronald F ; Jones, David H ; Morgan, Clive P..
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids.  1584 (2002)  1 - p. 20-30 , 2002
Link: https://doi.org/10.1016/s1388-1981(02)00265-2