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1 Ergebnisse
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Discovery of a Potent and Selective PI3Kδ Inhibitor (S)-2,4..:
Shukla, Manojkumar R.
;
Patra, Sukanya
;
Verma, Mahip
...
Journal of Medicinal Chemistry. 63 (2020) 23 - p. 14700-14723 , 2020
Link:
https://doi.org/10.1021/acs.jmedchem.0c01264
RT Journal T1
Discovery of a Potent and Selective PI3Kδ Inhibitor (S)-2,4-Diamino-6-((1-(7-fluoro-1-(4-fluorophenyl)-4-oxo-3-phenyl-4H-quinolizin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile with Improved Pharmacokinetic Profile and Superior Efficacy in Hematological Cancer Models
UL https://suche.suub.uni-bremen.de/peid=cr-10.1021_acs.jmedchem.0c01264&Exemplar=1&LAN=DE A1 Shukla, Manojkumar R. A1 Patra, Sukanya A1 Verma, Mahip A1 Sadasivam, Gayathri A1 Jana, Nirmal A1 Mahangare, Sachin J. A1 Vidhate, Prashant A1 Lagad, Dipak A1 Tarage, Anand A1 Cheemala, Murthy A1 Kulkarni, Chaitanya A1 Bhagwat, Shankar A1 Chaudhari, Vinod D. A1 Sayyed, Majid A1 Pachpute, Vipul A1 Phadtare, Ramesh A1 Gole, Gopal A1 Phukan, Samiron A1 Sunkara, Brahmam A1 Samant, Charudatt A1 Shingare, Manisha A1 Naik, Aditya A1 Trivedi, Sneha A1 Marisetti, Ajit Kumar A1 Reddy, Madhusudhan A1 Gholve, Milind A1 Mahajan, Nilesh A1 Sabde, Sudeep A1 Patil, Vinod A1 Modi, Dipak PB American Chemical Society (ACS) YR 2020 SN 0022-2623 SN 1520-4804 JF Journal of Medicinal Chemistry VO 63 IS 23 SP 14700 OP 14723 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.0c01264 DO https://doi.org/10.1021/acs.jmedchem.0c01264 SF ELIB - SuUB Bremen
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