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1 Ergebnisse
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Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyri..:
Johannes, Jeffrey W.
;
Balazs, Amber
;
Barratt, Derek
...
Journal of Medicinal Chemistry. 64 (2021) 19 - p. 14498-14512 , 2021
Link:
https://doi.org/10.1021/acs.jmedchem.1c01012
RT Journal T1
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1–DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs
UL https://suche.suub.uni-bremen.de/peid=cr-10.1021_acs.jmedchem.1c01012&Exemplar=1&LAN=DE A1 Johannes, Jeffrey W. A1 Balazs, Amber A1 Barratt, Derek A1 Bista, Michal A1 Chuba, Matthew D. A1 Cosulich, Sabina A1 Critchlow, Susan E. A1 Degorce, Sébastien L. A1 Di Fruscia, Paolo A1 Edmondson, Scott D. A1 Embrey, Kevin A1 Fawell, Stephen A1 Ghosh, Avipsa A1 Gill, Sonja J. A1 Gunnarsson, Anders A1 Hande, Sudhir M. A1 Heightman, Tom D. A1 Hemsley, Paul A1 Illuzzi, Giuditta A1 Lane, Jordan A1 Larner, Carrie A1 Leo, Elisabetta A1 Liu, Lina A1 Madin, Andrew A1 Martin, Scott A1 McWilliams, Lisa A1 O'Connor, Mark J. A1 Orme, Jonathan P. A1 Pachl, Fiona A1 Packer, Martin J. PB American Chemical Society (ACS) YR 2021 SN 0022-2623 SN 1520-4804 JF Journal of Medicinal Chemistry VO 64 IS 19 SP 14498 OP 14512 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.1c01012 DO https://doi.org/10.1021/acs.jmedchem.1c01012 SF ELIB - SuUB Bremen
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