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1 Ergebnisse
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Fragment Optimization of Reversible Binding to the Switch I..:
Bröker, Joachim
;
Waterson, Alex G.
;
Smethurst, Chris
...
Journal of Medicinal Chemistry. 65 (2022) 21 - p. 14614-14629 , 2022
Link:
https://doi.org/10.1021/acs.jmedchem.2c01120
RT Journal T1
Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor
UL https://suche.suub.uni-bremen.de/peid=cr-10.1021_acs.jmedchem.2c01120&Exemplar=1&LAN=DE A1 Bröker, Joachim A1 Waterson, Alex G. A1 Smethurst, Chris A1 Kessler, Dirk A1 Böttcher, Jark A1 Mayer, Moriz A1 Gmaschitz, Gerhard A1 Phan, Jason A1 Little, Andrew A1 Abbott, Jason R. A1 Sun, Qi A1 Gmachl, Michael A1 Rudolph, Dorothea A1 Arnhof, Heribert A1 Rumpel, Klaus A1 Savarese, Fabio A1 Gerstberger, Thomas A1 Mischerikow, Nikolai A1 Treu, Matthias A1 Herdeis, Lorenz A1 Wunberg, Tobias A1 Gollner, Andreas A1 Weinstabl, Harald A1 Mantoulidis, Andreas A1 Krämer, Oliver A1 McConnell, Darryl B. A1 W. Fesik, Stephen PB American Chemical Society (ACS) YR 2022 SN 0022-2623 SN 1520-4804 JF Journal of Medicinal Chemistry VO 65 IS 21 SP 14614 OP 14629 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.2c01120 DO https://doi.org/10.1021/acs.jmedchem.2c01120 SF ELIB - SuUB Bremen
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