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Overcoming Preclinical Safety Obstacles to Discover (S)-N-(..:
McBride, Christopher
;
Trzoss, Lynnie
;
Povero, Davide
...
Journal of Medicinal Chemistry. 65 (2022) 21 - p. 14721-14739 , 2022
Link:
https://doi.org/10.1021/acs.jmedchem.2c01250
RT Journal T1
Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor
UL https://suche.suub.uni-bremen.de/peid=cr-10.1021_acs.jmedchem.2c01250&Exemplar=1&LAN=DE A1 McBride, Christopher A1 Trzoss, Lynnie A1 Povero, Davide A1 Lazic, Milos A1 Ambrus-Aikelin, Geza A1 Santini, Angelina A1 Pranadinata, Rama A1 Bain, Gretchen A1 Stansfield, Ryan A1 Stafford, Jeffrey A. A1 Veal, James A1 Takahashi, Ryan A1 Ly, Justin A1 Chen, Shu A1 Liu, Liling A1 Nespi, Marika A1 Blake, Robert A1 Katewa, Arna A1 Kleinheinz, Tracy A1 Sujatha-Bhaskar, Swathi A1 Ramamoorthi, Nandhini A1 Sims, Jessica A1 McKenzie, Brent A1 Chen, Mark A1 Ultsch, Mark A1 Johnson, Matthew A1 Murray, Jeremy A1 Ciferri, Claudio A1 Staben, Steven T. A1 Townsend, Michael J. PB American Chemical Society (ACS) YR 2022 SN 0022-2623 SN 1520-4804 JF Journal of Medicinal Chemistry VO 65 IS 21 SP 14721 OP 14739 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.2c01250 DO https://doi.org/10.1021/acs.jmedchem.2c01250 SF ELIB - SuUB Bremen
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