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1
Multiparameter Lead Optimization to Give an Oral Checkpoint..:
Osborne, James D.
;
Matthews, Thomas P.
;
McHardy, Tatiana
...
Journal of Medicinal Chemistry. 59 (2016) 11 - p. 5221-5237 , 2016
Link:
https://doi.org/10.1021/acs.jmedchem.5b01938
RT Journal T1
Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)-5-((4-((Morpholin-2-ylmethyl)amino)-5-(trifluoromethyl)pyridin-2-yl)amino)pyrazine-2-carbonitrile (CCT245737)
UL https://suche.suub.uni-bremen.de/peid=cr-10.1021_acs.jmedchem.5b01938&Exemplar=1&LAN=DE A1 Osborne, James D. A1 Matthews, Thomas P. A1 McHardy, Tatiana A1 Proisy, Nicolas A1 Cheung, Kwai-Ming J. A1 Lainchbury, Michael A1 Brown, Nathan A1 Walton, Michael I. A1 Eve, Paul D. A1 Boxall, Katherine J. A1 Hayes, Angela A1 Henley, Alan T. A1 Valenti, Melanie R. A1 De Haven Brandon, Alexis K. A1 Box, Gary A1 Jamin, Yann A1 Robinson, Simon P. A1 Westwood, Isaac M. A1 van Montfort, Rob L. M. A1 Leonard, Philip M. A1 Lamers, Marieke B. A. C. A1 Reader, John C. A1 Aherne, G. Wynne A1 Raynaud, Florence I. A1 Eccles, Suzanne A. A1 Garrett, Michelle D. A1 Collins, Ian PB American Chemical Society (ACS) YR 2016 SN 0022-2623 SN 1520-4804 JF Journal of Medicinal Chemistry VO 59 IS 11 SP 5221 OP 5237 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.5b01938 DO https://doi.org/10.1021/acs.jmedchem.5b01938 SF ELIB - SuUB Bremen
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