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1 Ergebnisse
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Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2..:
Lelais, Gérald
;
Epple, Robert
;
Marsilje, Thomas H.
...
Journal of Medicinal Chemistry. 59 (2016) 14 - p. 6671-6689 , 2016
Link:
https://doi.org/10.1021/acs.jmedchem.5b01985
RT Journal T1
Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants for the Treatment of EGFR Mutant Non-Small-Cell Lung Cancers
UL https://suche.suub.uni-bremen.de/peid=cr-10.1021_acs.jmedchem.5b01985&Exemplar=1&LAN=DE A1 Lelais, Gérald A1 Epple, Robert A1 Marsilje, Thomas H. A1 Long, Yun O. A1 McNeill, Matthew A1 Chen, Bei A1 Lu, Wenshuo A1 Anumolu, Jaganmohan A1 Badiger, Sangamesh A1 Bursulaya, Badry A1 DiDonato, Michael A1 Fong, Rina A1 Juarez, Jose A1 Li, Jie A1 Manuia, Mari A1 Mason, Daniel E. A1 Gordon, Perry A1 Groessl, Todd A1 Johnson, Kevin A1 Jia, Yong A1 Kasibhatla, Shailaja A1 Li, Chun A1 Isbell, John A1 Spraggon, Glen A1 Bender, Steven A1 Michellys, Pierre-Yves PB American Chemical Society (ACS) YR 2016 SN 0022-2623 SN 1520-4804 JF Journal of Medicinal Chemistry VO 59 IS 14 SP 6671 OP 6689 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.5b01985 DO https://doi.org/10.1021/acs.jmedchem.5b01985 SF ELIB - SuUB Bremen
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