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1 Ergebnisse
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Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-..:
Planken, Simon
;
Behenna, Douglas C.
;
Nair, Sajiv K.
...
Journal of Medicinal Chemistry. 60 (2017) 7 - p. 3002-3019 , 2017
Link:
https://doi.org/10.1021/acs.jmedchem.6b01894
RT Journal T1
Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR
UL https://suche.suub.uni-bremen.de/peid=cr-10.1021_acs.jmedchem.6b01894&Exemplar=1&LAN=DE A1 Planken, Simon A1 Behenna, Douglas C. A1 Nair, Sajiv K. A1 Johnson, Theodore O. A1 Nagata, Asako A1 Almaden, Chau A1 Bailey, Simon A1 Ballard, T. Eric A1 Bernier, Louise A1 Cheng, Hengmiao A1 Cho-Schultz, Sujin A1 Dalvie, Deepak A1 Deal, Judith G. A1 Dinh, Dac M. A1 Edwards, Martin P. A1 Ferre, Rose Ann A1 Gajiwala, Ketan S. A1 Hemkens, Michelle A1 Kania, Robert S. A1 Kath, John C. A1 Matthews, Jean A1 Murray, Brion W. A1 Niessen, Sherry A1 Orr, Suvi T. M. A1 Pairish, Mason A1 Sach, Neal W. A1 Shen, Hong A1 Shi, Manli A1 Solowiej, James A1 Tran, Khanh PB American Chemical Society (ACS) YR 2017 SN 0022-2623 SN 1520-4804 JF Journal of Medicinal Chemistry VO 60 IS 7 SP 3002 OP 3019 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.6b01894 DO https://doi.org/10.1021/acs.jmedchem.6b01894 SF ELIB - SuUB Bremen
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