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1 Ergebnisse
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Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones..:
Wang, Zhen
;
Jiang, Xiangrui
;
Zhang, Xianglei
...
Journal of Medicinal Chemistry. 62 (2019) 10 - p. 4979-4990 , 2019
Link:
https://doi.org/10.1021/acs.jmedchem.9b00123
RT Journal T1
Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension
UL https://suche.suub.uni-bremen.de/peid=cr-10.1021_acs.jmedchem.9b00123&Exemplar=1&LAN=DE A1 Wang, Zhen A1 Jiang, Xiangrui A1 Zhang, Xianglei A1 Tian, Guanghui A1 Yang, Rulei A1 Wu, Jianzhong A1 Zou, Xiaoli A1 Liu, Zheng A1 Yang, Xiaojun A1 Wu, Chunhui A1 Shi, Jing A1 Li, Jianfeng A1 Suo, Jin A1 Wang, Yu A1 Zhang, Rongxia A1 Xu, Zhijian A1 Gong, Xudong A1 He, Yang A1 Zhu, Weiliang A1 Aisa, Haji Akber A1 Jiang, Hualiang A1 Xu, Yechun A1 Shen, Jingshan PB American Chemical Society (ACS) YR 2019 SN 0022-2623 SN 1520-4804 JF Journal of Medicinal Chemistry VO 62 IS 10 SP 4979 OP 4990 LK http://dx.doi.org/https://doi.org/10.1021/acs.jmedchem.9b00123 DO https://doi.org/10.1021/acs.jmedchem.9b00123 SF ELIB - SuUB Bremen
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