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Discovery of a Novel Class of Phosphodiesterase 10A Inhibit..:
Verhoest, Patrick R.
;
Chapin, Douglas S.
;
Corman, Michael
...
Journal of Medicinal Chemistry. 52 (2009) 16 - p. 5188-5196 , 2009
Link:
https://doi.org/10.1021/jm900521k
RT Journal T1
Discovery of a Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the Treatment of Schizophrenia†Coordinates of the PDE10A crystal structures have been deposited in the Protein Data Bank for compound 1 (3HQW), 2 (3HQY), 3 (3HQW) and 9 (3HR1)
UL https://suche.suub.uni-bremen.de/peid=cr-10.1021_jm900521k&Exemplar=1&LAN=DE A1 Verhoest, Patrick R. A1 Chapin, Douglas S. A1 Corman, Michael A1 Fonseca, Kari A1 Harms, John F. A1 Hou, Xinjun A1 Marr, Eric S. A1 Menniti, Frank S. A1 Nelson, Frederick A1 O'Connor, Rebecca A1 Pandit, Jayvardhan A1 Proulx-LaFrance, Caroline A1 Schmidt, Anne W. A1 Schmidt, Christopher J. A1 Suiciak, Judith A. A1 Liras, Spiros PB American Chemical Society (ACS) YR 2009 SN 0022-2623 SN 1520-4804 JF Journal of Medicinal Chemistry VO 52 IS 16 SP 5188 OP 5196 LK http://dx.doi.org/https://doi.org/10.1021/jm900521k DO https://doi.org/10.1021/jm900521k SF ELIB - SuUB Bremen
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