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Giant plasmid-encoded polyketide synthases produce the macr..:

Stinear, Timothy P. ; Mve-Obiang, Armand ; Small, Pamela L. C....
Proceedings of the National Academy of Sciences.  101 (2004)  5 - p. 1345-1349 , 2004
Link: https://doi.org/10.1073/pnas.0305877101