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Inositol polyphosphate multikinase is a physiologic PI3-kin..:

Maag, David ; Maxwell, Micah J. ; Hardesty, Douglas A....
Proceedings of the National Academy of Sciences.  108 (2011)  4 - p. 1391-1396 , 2011
Link: https://doi.org/10.1073/pnas.1017831108