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Axonal transport deficits and degeneration can evolve indep..:

Marinković, Petar ; Reuter, Miriam S. ; Brill, Monika S....
Proceedings of the National Academy of Sciences.  109 (2012)  11 - p. 4296-4301 , 2012
Link: https://doi.org/10.1073/pnas.1200658109