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The estrogen receptor antagonist ICI 182,780 can act both a..:

Movérare-Skrtic, Sofia ; Börjesson, Anna E. ; Farman, Helen H....
Proceedings of the National Academy of Sciences.  111 (2014)  3 - p. 1180-1185 , 2014
Link: https://doi.org/10.1073/pnas.1322910111