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Hybrid promiscuous (Hypr) GGDEF enzymes produce cyclic AMP-..:

Hallberg, Zachary F. ; Wang, Xin C. ; Wright, Todd A....
Proceedings of the National Academy of Sciences.  113 (2016)  7 - p. 1790-1795 , 2016
Link: https://doi.org/10.1073/pnas.1515287113