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Lipiarmycin targets RNA polymerase and has good activity ag..:

Kurabachew, M. ; Lu, S. H. J. ; Krastel, P....
Journal of Antimicrobial Chemotherapy.  62 (2008)  4 - p. 713-719 , 2008
Link: https://doi.org/10.1093/jac/dkn269