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Mutations in PLCE1 are a major cause of isolated diffuse me..:

Gbadegesin, R. ; Hinkes, B. G. ; Hoskins, B. E....
Nephrology Dialysis Transplantation.  23 (2007)  4 - p. 1291-1297 , 2007
Link: https://doi.org/10.1093/ndt/gfm759