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Mast Cell Degranulation Breaks Peripheral Tolerance:

De Vries, V.C. ; Wasiuk, A. ; Bennett, K.A....
American Journal of Transplantation.  9 (2009)  10 - p. 2270-2280 , 2009
Link: https://doi.org/10.1111/j.1600-6143.2009.02755.x