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The peptide-based drug cortexin inhibits brain caspase-8:

Yakovlev, A. A. ; Lyzhin, A. A. ; Khaspekov, L. G...
Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry.  11 (2017)  2 - p. 134-138 , 2017
Link: https://doi.org/10.1134/s1990750817020111