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Plasma endothelin and renal endothelin are two distinct sys..:

Serneri, G. G. ; Modesti, P. A. ; Cecioni, I....
American Journal of Physiology-Heart and Circulatory Physiology.  268 (1995)  5 - p. H1829-H1837 , 1995
Link: https://doi.org/10.1152/ajpheart.1995.268.5.h1829