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CFH and ARMS2 genetic risk determines progression to neovas..:

Vavvas, Demetrios G. ; Βάββας, Δημήτριoς Γ. ; Small, Kent W....
Proceedings of the National Academy of Sciences of the United States of America.  115 (2018)  4 - p. E696-E704 , 2018
Link: https://www.jstor.org/stable/26506495