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For now, it's unethical to use human challenge studies for ..:

Kahn, Jeffrey P. ; Henry, Leslie Meltzer ; Mastroianni, Anna C...
Proceedings of the National Academy of Sciences of the United States of America.  117 (2020)  46 - p. 28538-28542 , 2020
Link: https://www.jstor.org/stable/26970964