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Conserved disulfide bond is not essential for the adenosine..:

Naranjo, Andrea N. ; Chevalier, Amy ; Cousins, Gregory D....
Biochimica et Biophysica Acta (BBA) - Biomembranes.  1848 (2015)  2 - p. 603-614 , 2015
Link: https://doi.org/10.1016/j.bbamem.2014.11.010